Biosan

BioSan Orbital Shaker-Incubator ES-20-80C with Cooler

The ES-20-80C shaker incubator is a professional instrument for biotechnology and pharmaceutical laboratories.
Typical applications include cultivation of microbial and cell cultures, protein expression, solubility studies, general mixing and various other applications in the fields of biology and chemistry.

The unit is equipped with a newly developed triple-eccentric mechanism for platform movement, which ensures outstanding balancing characteristics, superior reliability and quiet operation.
The stability of the unit during heavy mixing operations allows up to 3 units to be stacked to save space.
The new display and easy-to-use interface provide clear, intuitive control of parameters and also allow for ongoing logging, storage and display of data.
Additional features such as the imbalance sensor and automatic thermostat failure detection make this shaker incubator a modern and safe product.
The Bluetooth PC interface allows data management, data logging, parameter control-profiling with specially developed software.

The built-in heat-resistant collectorless fan provides precise temperature distribution in the chamber (from 12.5 °C below ambient to +80 °C). In addition, excellent sample temperature uniformity of ±0.2 °C at 37 °C is achieved. The interior of the chamber is made of stainless steel. State-of-the-art motor, heat-insulating materials and parameter PID control reduce energy consumption and make the shaker incubator an extremely energy-efficient device despite its size.

BioSan Orbital Shaker PSU-10i exceeds its ancestor OS-10 not only in design but also by having a direct drive system, a brushless motor with guaranteed service life up to 35 000 hours and an automatic loading balancing system. These innovations make the new series of shakers even more reliable, especially for the long non-stop operation, and essentially expands the product performance range in both high and low limits.

The shaker is designed for application both in small specialised biotechnological laboratories and in large multidisciplinary laboratories: a choice of five interchangeable platforms provides the possibility of performing various procedures and techniques.

Shaker can be used in cold rooms or incubators, operating at ambient temperature range +4°C to +40°C. Low voltage external power supply (12 V) provides electrical safety in humid environment.


Without platform, please order separately!

BioSan Orbital Shaker-Incubator ES-20-80, without platform

ES-20-80 shaker-incubator for biotechnological and pharmaceutical laboratories is a professional category equipment.
The typical applications include - microbial and cell culture cultivation, protein expression, solubility studies, general mixing, as well as other various applications in the fields of biology and chemistry.

The unit is equipped with a newly developed triple eccentric mechanism for platform motion that provides supreme balancing characteristics, superior reliability and quiet operation. The achieved stability of the unit during vigorous mixing allows for stacking installation of up to 3 units which enables to save space. The new display and easy to use user interface provide a clear and intuitive control of parameters and also allow data logging, storage and display over time. Additional features like out of balance sensor and automatic thermostat failure detection make this shaker-incubator an advanced and safe product. Bluetooth connectivity to PC allows for data management, data logging, parameter control and profiling in the included software.

A built-in heat-resistant brushless fan provides precise temperature distribution inside the chamber (from 10 °C above ambient up to +80 °C). Additionally, excellent sample temperature uniformity of+0.3 °C at 37 °C is achieved. The inner chamber is made of stainless steel. State-of-the-art motor, thermal insulation materials and parameter PIDcontrol decrease the energy consumption and make the shaker-incubator highly energy efficient despite its relatively large size.

BioSan Photometer DEN-600

DEN-600 is a compact, portable, rechargeable, battery-operated photometer.
DEN-600 consists of an optical system with a wavelength of 600 nm, which can be used for the following:
1) OD600 method to estimate the total number of cells,
2) McFarland (McF) turbidity measurement method,
3) Bradford protein assay method to measure protein concentration.

The instrument serves as a cost-effective alternative to a spectrophotometer commonly used for these applications.
Because DEN-600 is battery-powered and compact, it can be conveniently placed in a biosafety cabinet, an anaerobic chamber or quickly moved to another laboratory space. In addition, the vessel holding mechanism allows it to accept standard 10 mm path, round-bottomed, conical vials or falcon tubes, allowing absorbance and turbidity to be measured in Abs, OD or McF units.

USB connectivity and DEN software allow data transfer, data processing and calculation, software calibration for the Bradford protein assay method or custom calibration for a specific applicable vessel and custom turbidity standards.

Common applications are:

• Measurement of cell concentration
• Evaluation of cell growth data
• Evaluation of logarithmic growth phase for induction of microbial cells
• Preparation of competent cells
• Protein quantification method according to Bradford
• Antibiotic susceptibility tests
• Inhibition tests

Thermo-Shaker PST-100HL is designed for shaking and thermostating two standard 96-well microplates.

A multisystem principle, used in design of the shaker-thermostat, allows operating it as 3 independent devices:

• Incubator
• Microplate shaker
• Shaker-Thermostat

A distinctive feature of Biosan Plate Shaker-Thermostat is the patented by the company two-side heating of microtest plates, which allows achieving exact correspondence of the set and actual temperature in wells of the microtest plates.

The Shaker provides:

• Gentle or vigorous shaking of samples
• Regulation, stabilisation and indication of rotation speed
• Even rotation amplitude throughout the Thermo-Shaker platform
• Setting and indication of the required operation time
• Automatic stop of the platform motion after expiration of the set time
• Setting and indication of the required temperature on the platform

Application fields:

• Cytochemistry - for in situ reactions
• Immunochemistry - for immunofermentative reactions
• Biochemistry - for enzyme and protein analysis
• Molecular biology - for micro array analysis

BioSan Multi-Shaker "3D Sunflower" Multi Bio 3D provides realization of several types of motion in one module. This option of Biosan instruments essentially extends possibilities and enhances efficiency of preparation of test samples as well as allows selecting the mixing type according to individual requirements.

The multi-shaker is designed for a variety of applications: hybridization reactions, cell growing, gel washing, soft extraction and homogenisation of biological components in solutions.

Microprocessor control allows:

1. Orbital 3D rotation of the platform
2. Reciprocal 3D motion (of ping-pong type)
3. Soft vibrating rocking

These three motion types can be performed separately, pairwise and in cycles, periodically repeating the sequence of three motion types. The shaker is designed for laboratories with increased demands for quality of mixing, extraction and cell growing processes.

Non-slip rubber mat located on the shaker platform provides stable position for vessels during shaking.

Shaker can be used in cold rooms or incubators, operating at ambient temperature range +4°C to +40°C. Low voltage external power supply (12 V) provides electrical safety in humid environment.

BioSan Multi-Rotator Multi Bio RS-24 performs several motion types in one module. Microprocessor control allows performing not only Vertical rotation of the platform, but also Reciprocal rotation as well as Vibration. These three motion types can be performed separately, pairwise and in cycles, periodically repeating the sequence of three motion types. Multi-rotation option of Biosan instruments substantially expands possibilities and enhances efficiency of sample preparation for the examined materials and allows adjusting the mixing procedure according to individual tasks.

Multi-Rotator can be used for variety of applications in modern life science laboratories: for hybridization reactions, cell growing, soft extraction and homogenisation of biological components in solutions, as well as for reactions of binding and washing of magnetic particles.

Multi-Rotator can be used in cold rooms or incubators, operating at ambient temperature range +4°C to +40°C. Low voltage external power supply (12 V) provides electrical safety in humid environment.

Programmable BioSan Rotator Multi RS-60 performs several motion types in one module. Microprocessor control allows performing not only Vertical rotation of the platform, but also Reciprocal rotation as well as Vibration. These three motion types can be performed separately, pairwise and in cycles, periodically repeating the sequence of three motion types. Multi-rotation option of Biosan instruments substantially expands possibilities and enhances efficiency of sample preparation for the examined materials and allows adjusting the mixing procedure according to individual tasks.

Multi-Rotator can be used for variety of applications in modern life science laboratories: for hybridization reactions, cell growing, soft extraction and homogenisation of biological components in solutions, as well as for reactions of binding and washing of magnetic particles.

The rotor PRS-48 is included.

This device is a new orbital shaker in the multi-functional mixing device range. It differs from its ancestor Multi PSU-20 not only in a new external design but also by having a direct drive system and a brush-less motor with service life up to 35 000 hours.This orbial shakeris an ideal instrument for different biopharmaceutical and biomedical profile laboratories.

The orbital shaker PSU-20i is designed for application both in small specialised laboratories and in large multidisciplinary laboratories: a choice of nine different interchangeable platforms provides possibility of performing various procedures and techniques. Special attention should be paid to a multilevel platform, which allows accommodation of a large number of various microplates, Petri dishes, cultural bags and other low containers.

Operation of the instrument is noiseless and reliable.It can provide stable continuous mixing for up to 7 daysand can be used in cold rooms or incubators, operating at ambient temperature range +5°C to +40°C. Low voltage external power supply (12 V) provides electrical safety in humid environment.

Motion types Orbital Shaker PSU-20i:

The Shaker is multifunctional; it provides three motion types, which can be performed separately, pairwise and sequentially in repeated cycles.

A) Orbital motion = Simple orbital motion with an option of shifting direction (clockwise/anti-clockwise) after set time

• Regulated speed 20 - 250 RPM
• Motion timer 0 - 250 sec (for switching to the next motion in the cycle or for changing direction on the opposite)
• General operation timer 1 min - 96 hours (increment 1 min)

B) Reciprocating Rotation motion = Orbital motion with shifting direction of rotation

• Regulated speed 0 - 250 RPM (same as in Orbital motion)
• Motion timer 0 - 250 sec (for switching to the next motion in the cycle)
• Regulated turning angle 0° - 360° (increment 30°)
• General operation timer 1 min - 96 hours (increment 1 min)

C) Vibration mode = High speed, low amplitude motion

• Regulated turning angle 0° - 5° (increment 1°).
• Motion timer 0 - 5 sec (for switching to the next motion in the cycle)
• General operation timer 1 min 96 hours (increment 1 min)

Without platform, please order separately!

BioSan real-time PCR detection system BioQuant-96
The latest addition to the Biosan family of molecular diagnostic products.

It has adopted innovative thermoelectric refrigeration technology, brand new light source and light path design.
Top detection allows the use of a variety of consumables - 0.2 tubes, 8-tube strips, and semi-rimmed and non-rimmed 96-well PCR plates.
The unique constant current performance and 6-zone independent temperature control method ensure faster, more correct and stable quantitative fluorescence analysis while maintaining excellent performance with the lowest possible power consumption.

The instrument is available in 5-channel and 6-channel configurations.
Meanwhile, features such as independent temperature control, low-temperature sample storage at 4 °C and FAST mode for faster cycling have been added (confirm reagent compatibility with FAST mode).

BioQuant-96 comprehensively realises automatic gain adjustment and improves the user experience.
It will fully meet the requirements of scientific research laboratories and be registered as a Class I (A) medical device in the EU.
It will also fully meet the requirements of any diagnostic laboratory.

BioSan RTS-1C - Personal Bioreactor

RTS-1C is personal bioreactor which provides ''Reverse-Spin'' type of agitation and logging of microbial growth in 50 ml tubes in real time.

Features:

• innovative mixing due to reverse spinning of the sample around its own axis
• due to innovative mixing technology it is possible to measure optical density of the probe in real time
• Software has been developed to store, display and analyse the data in real time
• RTS-1C is compact device with low profile and small footprint for personal application
• Temperature control allows to use RTS-1C as an incubator, e.g. for cell growth
• RTS-1C has a function of active cooling and temperature profiling via software
• the ability to change parameters such as temperature, RPM and ''Reverse-Spin'' frequency, allows to achieve consistency and reproducibility of results
• programmable Cycling/profiling of cultivation parameters such as temperature, RPM, ''Reverse-Spin'' frequency
• the ability to remotely monitor the process of cultivation while home or using a mobile phone

Software features:

• Real-Time cell growth logging
• 3D graphical representation of OD or growth rate over time over unit
• Pause option
• Save/Load option
• Report option: PDF and Excel
• Connect up to 12 units simultaneously
• Remote monitoring option (requires internet connection)
• Cycling/Profiling options
• user calibration options for any microorganism

Typical applications:

• Bacterial cultivation with real time growth kinetics
• Strain screening
• Temperature stress and fluctuation experiments
• Media screening and optimization
• Synthetic and systems biology
• Inhibition and toxicity tests
• Strain quality control

BioSan S-Bt Smart Biotherm, Compact CO₂ Incubator

S-Bt Smart Biotherm is designed for work in the areas of cell biology (operations with animal cell cultures and tissues), molecular biology (DNA-RNA reaction analysis, hybridization reactions), biotechnology (synthesis of target proteins and other molecules), immunology (synthesis of antibodies and other proteins of immune system).

Unit provides a six-sided heating: the heating elements are located on the walls and on the door, thus providing excellent uniform temperature distribution, regardless of external factors, such as ambient temperature and positioning of the device.

Built-in infrared CO₂-sensor allows accurate control of the CO₂ level. The sensor makes measurement non-sensitive to changes in temperature and humidity inside the incubator.

The chamber is made of stainless steel with smoothed seams to minimize contamination and to facilitate cleaning.

S-Bt is equipped with a UV air recirculation system - 1 UV lamp and a fan are mounted behind the rear wall, providing decontamination of the working volume.

A convenient access port is built in the wall of the incubator for easy output of wire sensors or devices' installed inside. The access port is heated independently to prevent formation of condensate.

Unit is equipped with error tracing and alarm systems, which significantly lower potential risks during operation.

Unit is equipped with a ''black box'' system that records temperature, humidity and CO₂ levels, as well as statuses for door opening, UV lamp, fan and errors, to the inner memory.

Bluetooth connection to PC is available.

The ES-20 is a compact bench-top Shaker-Incubator used for mixing of biological liquids as well as the incubation and cultivation of biological liquids according to the operator set program.

Built-in microprocessor thermocontroller provides constant temperature control in the incubator chamber. Forced heated air circulation inside the transparent plexiglas chamber guarantees even temperature distribution. Dismountable construction makes transportation easy.

Orbital shaking is controlled by the digital tachometer (rpm) and digital timer independently of the temperature. The unit is equipped with the direct-drive system ensuring most reliable stable long-time operation (up to 30 day nights).

The device is extremely easy to operate, with very straightforward setup of temperature, speed and time, using the two line set-up and status display, which clearly indicates both set and actual values for each of the three parameters.

Five interchangeable platforms allow using the shaker for:

• Growing cell cultures in flasks and other laboratory glassware
• Extracting tissue samples at physiological temperatures
• Other sample preparation processes

Upgraded model. Fast acceleration for shorter operation time and increased mixing efficiency.
Calibration function for flexibility of temperature control in different tubes.
New block - SC-24N for 24 x 1,5 ml microtubes.

Thermo-Shaker TS-100 provides mixing and temperature control of samples in microtest tubes or PCR plate. Functions of heating and mixing can be performed both simultaneously and independently, i.e. the unit implements three devices in one:

1. Shaker
2. Thermostat
3. Thermoshaker

The thermoshaker is used for DNA analysis sample preparation, for extraction of proteins, polysaccharides, lipids and other cellular components.

Heating source is a printed heating board (12 V). Mixing is provided by movement of orbital type.

The instrument is applicable in:

• DNA analysis, DNA extraction
• Biochemical study of enzymatic reactions and processes
• Extraction of metabolites from cellular material

Temperature calibration function:
Using the temperature calibration function, the user can calibrate the device to ± 6% of the selected temperature, to compensate differences in the thermal behavior of containers of different manufacturers.

Note: Thermoblocks/attachments are not included in the delivery! Please order them separately.

Upgraded model. Fast acceleration for shorter operation time and increased mixing efficiency.
Calibration function for flexibility of temperature control in different tubes.
New block - SC-24NC for 24 x 1,5 ml microtubes.

Thermo-shaker TS-100C provides mixing and temperature control of samples in microtest tubes or PCR plate. This model of thermo-shaker differs from TS-100 with a possibility of cooling samples down to +4°C. Features of TS-100C meet the highest expectations of users according to many parameters:

• Fast reaching of specified mixing speed and maintenance of equal amplitude of rotation throughout the Thermo-shaker block
• Stability of maintaining the preset temperature in a wide range throughout the Thermo-shaker?s block surface
• LCD display indicates preset and current values of temperature, speed and time of operation
• Quiet motor operation, compact size, prolonged service life.

Functions of heating and mixing can be performed both simultaneously and independently.

There are six (6) heating and cooling blocks available, including a block with a plastic lid for the PCR-plates. All blocks are mutually interchangeable and can be easily installed on thermo-shaker.

The instrument is applicable in:

• Genetic analysis, extraction of DNA, RNA and further sample preparation
• Biochemical study of enzymatic reactions and processes
• Extraction of metabolites from cellular material

Temperature Calibration Function
With the help of the temperature calibration function the user can calibrate the unit approx. ±6% of the selected temperature to compensate differences in the thermal behaviour of tubes from different manufacturers.

Note: Thermoblocks/attachments are not included in the delivery! Please order them separately.

BioSan Thermoshaker TS-100C SmartThermoshaker with cooler for microtubes and PCR plates The

TS-100C Smart thermoshaker offers intensive mixing and temperature control for samples in microtubes or PCR plates. With the new model you can control the instrument in the following modes:

• 1. manual via the user interface.
• 2. via a computer program with Bluetooth connection

The TS-100C Smart features meet the highest user expectations in terms of many parameters:

• Fast achievement of the specific mixing speed and maintenance of the same rotation amplitude in the whole thermoshaker block;
• 2. maintaining a stable preset temperature within a wide range over the entire surface of the thermoshaker block;
• 3. LCD display shows the preset and actual operating temperature, speed and time values
• 4. quiet motor operation, compact size, extended life.

Heating and mixing can be carried out simultaneously or independently.

Five heating and cooling blocks are available, including one block with plastic flap for the PCR plates. All blocks are interchangeable and can be easily installed on the thermoshaker.

Fields of application of the instrument:

• Genetic analysis - for extraction of DNA, RNA and other sample preparation methods;
• Biochemical studies of enzymatic reactions and processes;
• Extraction of metabolites from cell material.

Temperature Calibration
Function The temperature calibration function allows the user to calibrate the instrument to ±6% of the selected temperature to compensate for differences in thermal performance of tubes from different manufacturers.

TS-100C smart software functions

• Wireless connection to PC
• Connect up to 7 units to one PC
• Remote control of speed, temperature, time and sound signal
• Create profiling programs
• Visualization of diagrams (temperature over time, speed over time)
• Data export in Excel and CSV formats
• Error messages/fault diagnosis

Note: Thermoblocks/attachments are not included in the scope of delivery! Please order these separately.

BioSan UV air flow cleaner UVR-Mi are applicable for UV air inactivation in research laboratory rooms, waiting rooms in outpatients departments, surgeries and veterinary stations.

Advantages:

• Device is the upgraded more powerful model of UV air flow cleaner
• Active desinforming antimicrobial action of two factors - UV radiation and catalytic action of titanium oxide on biological molecules of viruses, germs and other toxic organic molecules
• Full user protection from direct UV radiation
• Two operation modes - short time (under timer control) and continuous operation
• Indication of UV lamps working hours

Recirculator fixation:

• Convenient fixation on walls (standard)
• Mounting on a movable tripod (optional)

BioSan UVC/T-M-AR PCR cabinet

The BioSan UVC/T-M-AR PCR cabinet offers a reliable and safe solution for all PCR setups and other demanding molecular biology applications. Thanks to its dual UV disinfection system, the device enables effective decontamination of DNA/RNA impurities and other contaminants. Especially in highly sensitive laboratory environments, this cabinet facilitates daily work by providing a low-germ, controlled work surface while optimising energy consumption. Compared to many commercially available alternatives, it impresses with its integrated UV recirculation fan, which circulates the entire cabinet volume several times per hour, ensuring particularly thorough air decontamination without direct UV exposure for laboratory staff.

Efficient UV technology and sophisticated design

This model impresses with an innovative dual UV system: a 25 W UV-C lamp in the wavelength range of 253.7 nm ensures intensive, ozone-free sterilisation of surfaces and work materials, while a separate UV recirculator cleans the air of bacteria, viruses and nucleic acid fragments. The open UV lamp switches off automatically as soon as the transparent front screen is opened - a safety feature that effectively protects operators from unwanted radiation. In addition, a digital touchscreen (3.5 inches) allows precise control of the exposure time, with direct UV exposure adjustable between 1 minute and 24 hours.

The hard-wearing stainless steel rear and side panels are extremely resistant to disinfectants. Front and side panels made of heat and UV-resistant glass (EUROGLASS) ensure a clear view inside, with light transmission of up to 95 per cent. An 8 mm thick upper front and a 4 mm thick transparent screen increase overall safety without compromising user-friendliness. Another advantage is the integrated, extremely long-lasting LED lighting (8 W), which creates a bright working environment and saves energy.

Important key technical data at a glance:
- Built-in UV-C lamp (25 W, TUV 25W 1SL/25)
- Patented UV recirculator with an efficiency of over 99 per cent per hour
- Timer control of the UV lamp from 1 minute to 24 hours (one-minute steps)
- Automatic switch-off of the open UV lamp when the shade is open
- Integrated socket (max. 1000 W) and cable inlet inside the cabinet
- Robust, low-noise fan system and only 64 W power consumption

Other design features such as an ergonomic handle, the sturdy metal frame structure and the UV-resistant surface materials make the appliance ideal for demanding everyday laboratory work. If you need additional storage space, you can combine it with the mobile T-4 tables, height-adjustable LT-120, LT-150 and LT-180 tables. These can be easily moved or adapted to the individual working position.

Certifications, standards and safety

Although PCR cabinet systems do not generally require separate DIN or CE classification, as is the case with larger safety cabinets, the device fulfils all relevant safety requirements for standard laboratory operation. According to the manufacturer, the transparent protective screen blocks over 96 per cent of UV radiation. In combination with the automatic UV switch-off system, the user is therefore optimally protected. The materials used - including the UV-resistant plastic and hardened glass - also prevent material fatigue.

Practical application examples

- Preparation of PCR preparations for DNA and RNA amplification, for example in diagnostic test series
. - Creation of sophisticated qPCR settings in research departments to prevent cross-contamination
- Preparation of reagents and master mixes for molecular biological analyses (e.g. multiplex PCR).
- Sterile storage of pipettes, Eppendorf tubes and consumables, which should remain free of microorganisms.

Thanks to its compact format and the optional T-4 table solution, the cabinet fits easily into small or medium-sized rooms. The integrated connector panel allows the operation of smaller laboratory devices such as vortexers or centrifuges without the need for separate extensions.

FAQs

How long should the UV lamp remain switched on?

In most cases, 15 to 30 minutes is sufficient for surface decontamination. For heavier contamination or sterile PCR setups, the time can be set up to 60 minutes or longer.

Can I operate several PCR ovens in parallel?

Yes, this is possible without any problems. Just make sure you have sufficient power capacity and a functioning exhaust air or room ventilation system if several appliances are running.

Is a filter change necessary

The patented UV recirculation fan sterilises the air without the need for traditional HEPA or activated carbon filters. Maintenance costs are mainly limited to changing the lamps at the end of their service life.

How often does the UV lamp need to be changed?

The installed UV-C lamp has a service life of around 9,000 hours. The integrated timer informs the user of the remaining lamp time so that it can be replaced in good time.

Conclusion

This PCR cabinet combines sophisticated UV technology, robust stainless steel construction and user-friendly touchscreen control to make laboratory protocols efficient and safe. The efficient combination of open UV radiation and continuous air circulation ensures comprehensive decontamination of surfaces and equipment. With a space-saving design, practical sockets and high transparency through glass elements, it becomes a powerful solution that delivers optimal results in both diagnostic laboratories and research environments and significantly reduces the risks of contamination.